Vitamin C deficiency could lead to symptoms of copper deficiency. Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) -- Both aspirin and NSAIDs can lower the amount of vitamin C in the body because they cause more of the vitamin to be lost in urine. The likelihood of drug interactions increases as the number of drugs being taken increases. The study is created by eHealthMe based on reports of 650 people who take Doxycycline and Vitamin c from the FDA, and is updated regularly. The B12 in food is unavailable until the acid and enzymes in the stomach release it from its bound form. Once free, B12 combines with a substance known as intrinsic factor and is absorbed from the intestines into the bloodstream. Highly clinically significant. There is 1 alcohol/food interaction with Vitamin C (ascorbic acid) Protease inhibitors.Oral use of vit… If you are being treated with any of the following medications, you should not use vitamin C supplements without first talking to your health care provider. Possible interactions include: 1. 1999;69:3173-178. Learn about drug interactions between ascorbic acid oral and aspirin-acetaminophen oral and use the RxList drug interaction checker to check drug combinations. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. ... J. D. Interaction of vitamin C and iron. 1981;23(VI):33-37. Look up a drug to see which other drugs it interacts with and how serious those interactions are. Possible Interactions with: Vitamin A (Retinol). -- Both aspirin and NSAIDs can lower the amount of vitamin C in the body because they cause more of the vitamin to be lost in urine. This systematic review of the literature was conducted to evaluate the extent to which drugs affect vitamin D status or supplementation alters drug effectiveness or toxicity in humans. Low levels of vitamin C can result in a condition called scurvy.Scurvy may cause symptoms such as rash, muscle weakness, joint pain, tiredness, or tooth loss. Abbott Pharmaceutical, Abbott Park, IL. For a reader-friendly overview of Vitamin C, see our consumer fact sheet on Vitamin C.. Introduction. 3. If you regularly take aspirin or NSAIDs, talk to your doctor before taking more than the recommended daily allowance of vitamin C. Acetaminophen (Tylenol) Ascorbic acid should be administered cautiously and dosages modified in patients with G6PD. There are 4 disease interactions with Vitamin C (ascorbic acid) which include: hemolysis; kidney stones; sodium; dialysis Ascorbic acid can acidify urine resulting in precipitation of urate, cystine, or oxalate stones. content is best viewed in IE9 or above, Firefox and Google Chrome browser. Applies to: Nephrolithiasis. Select one or more newsletters to continue. Content is best viewed in IE9 or above, Firefox and Google Chrome browser. 2. Int J Vitam Nutr Res. Drug interactions contribute to the cost of healthcare because of the costs of medical care that are required to treat probl… We comply with the HONcode standard for trustworthy health information -. This is a fact sheet intended for health professionals. Reviewed By: Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Taking vitamin C can increase your absorption of aluminum from medications containing aluminum, such as phosphate binders. Because of this, there is a potential for interactions with some common drugs. A diet high in vitamin C led to increased percent of absorption of sodium selenite and retention of the absorbed selenium. Vitamin B12. Taking an aspirin a day to prevent heart attacks and strokes causes blood loss via the digestive tract on the order of about a tablespoon per day which results in iron loss. Micronutrient Interactions with other minerals or vitamins Interactions Symbol … Vitamins and Drug Interactions Vitamin A: Vitamin A is a fat-soluble vitamin found in everyday foods, including liver, yellow-orange fruits and vegetables such as carrots, margarine, milk, and dark green, leafy vegetables such as spinach. Large doses of ascorbic acid have lead to hyperoxaluria in 5% of patients. Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) 3. There is concern that use of antioxidants, such as vitamin C, during chemotherapy might reduce the drug's effect. Whenever two or more drugs are being taken, there is a chance that there will be an interaction among the drugs. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. There are 4 disease interactions with Vitamin C (ascorbic acid): Moderate Potential Hazard, Moderate plausibility. Vitamin C (ascorbic acid) drug interactions. Moderately clinically significant. Schumann K. Interactions between drugs and vitamins at advanced age. Drug interactions are reported among people who take Vitamin c and Coq10. However, if you take warfarin or another blood thinner, talk to your doctor before taking vitamin C or any other supplement. USES: Ascorbic acid (vitamin C) is used to prevent or treat low levels of vitamin C in people who do not get enough of the vitamin from their diets.Most people who eat a normal diet do not need extra ascorbic acid. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Aluminum. Warfarin (Coumadin) Tetracycline -- The study is created by eHealthMe based on reports of 1,065 people who take Tamsulosin and Vitamin c from the FDA, and is updated regularly. Conditions: a high amount of oxalic acid in urine iron metabolism disorder causing increased iron storage sickle cell anemia anemia from pyruvate kinase and G6PD deficiencies Aluminum.Taking vitamin C can increase your absorption of aluminum from medications containing aluminum, such as phosphate binders. If you are undergoing chemotherapy, do not take vitamin C or any other supplement without talking to your oncologist. Usually avoid combinations; use it only under special circumstances. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. In addition, high doses of vitamin C can cause more of these drugs to stay in the body, raising the levels in your blood. The study is created by eHealthMe based on reports of 1,053 people who take Vitamin c and Coq10 from … 4. Drug interactions overview Ascorbic acid may decrease effects of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin; if antibiotic efficacy is suspected, discontinue ascorbic acid Limited case reports have suggested interference of ascorbic acid with anticoagulation effects of warfarin; monitor But taking vitamin C along with the antidepressant drug citalopram does not reduce depression symptoms in adults better than citalopram alone. Vitamin C and Drug Interactions. Ascorbic Acid is used to prevent or treat low levels of vitamin C in people who do not get enough of the vitamin from their diets. Oral estrogens can also decrease the effects of vitamin C in the body. Take large doses of vitamin C in divided amounts because the body uses only what is needed at a particular time and excretes the rest in urine. When oral administration is not feasible or when malabsorption is suspected, the drug may be administered IM, IV, or subcutaneously. Avoid combinations; the risk of the interaction outweighs the benefit. The study is created by eHealthMe based on reports of 4,521 people who take Vitamin c and Omeprazole from the FDA, and is updated regularly. Megadoses can interfere with absorption of vitamin B12. Some very early research suggests that vitamin C might help protect against stomach upset that aspirin and NSAIDs can cause. Omray A. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Aluminum-containing antacids Drug interactions are reported among people who take Vitamin c and Omeprazole together. Smith EC. Vitamin D is essential to maintaining a healthy immune system and strong bones. Therefore, people who take several drugs are at the greatest risk for interactions. The sodium content should be considered when used in patients with sodium restricted diets and conditions require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. 4. Evaluation of pharmacokinetic parameters of tetracylcine hydrochloride upon oral administration with vitamin C and vitamin B complex. Yet, the potential for drug-vitamin D interactions is rarely considered. Hindustan Antibiot Bull. It might also be useful in preventing many chronic diseases including cancer 1.Vitamin D regulates the amount of minerals such as calcium in the body 1. 2. If you take nitrate medications, talk to your doctor about whether you should take vitamin C. Oral contraceptives (birth control pills) and hormone replacement therapy (HRT) Other antibiotics in the same family include minocycline (Minocin) and doxycycline (Vibramycin). Drug interactions are reported among people who take Vitamin c and Lipitor. Protease inhibitors Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Applies to: hemodialysis, There are 27 drug interactions with Vitamin C (ascorbic acid), There is 1 alcohol/food interaction with Vitamin C (ascorbic acid). -- Vitamin C can cause a rise in estrogen levels when taken with these drugs, particularly if you are deficient in vitamin C to begin with and start taking supplements. Clinical monitoring of urinalysis for pH and crystal formation is recommended. Vitamin B6 deficiency can induce anemia, abnormal brain activity, mood disorders, muscle twitching and seizures (see references 5). -- There have been rare reports of vitamin C interfering with the effectiveness of this blood thinning medication. Chemotherapy drugs Note: Vitamin C increases the absorption of iron when taken at the same time as iron-rich foods. Vitamin B12 is probably the most well-known nutrient to interact with the drug Metformin. Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. Some of the medicines that may lead to vitamin C drug interactions include: Aluminum products (including many antacids ), such as Mylanta ® Chemotherapy Estrogens, including hormone replacement therapy ( HRT) and hormonal contraceptives (such as birth control pills) Protease inhibitors, such as: "Product Information. Estrogen.Taking vitamin C with oral contraceptive or hormone replacement therapy might increase your estrogen levels. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Vitamin B-12 is also added to some foods and is available as an oral supplement. Ascorbic acid (vitamin c) is usually administered orally. Selenium. Nitrate medications for heart disease Ascorbic acid preparations contain sodium. Vitamin B6 deficiency also weakens your immune system. There are 27 drug interactions with Vitamin C (ascorbic acid) Vitamin C (ascorbic acid) disease interactions. 20 mg. Interactions Individual interactants: Cemill (ascorbic acid)." Acute hemolysis following administration of high doses of ascorbic acid in patients with glucose-6-phosphate deficiency (G6PD) has been reported. Iron. Possible interactions include: 1. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. -- Vitamin C appears to slightly lower levels of indinavir (Crixivan), a medication used to treat HIV and AIDS. Moderate Potential Hazard, Moderate plausibility. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Chemotherapy.There is concern that use of antioxidants, such as vitamin C, during chemotherapy might reduce the drug's effect. DOSAGE AND ADMINISTRATION. Review provided by VeriMed Healthcare Network. Ascorbic acid should be administered cautiously and dosages modified in patients predisposed to renal stones. 700 units, vitamin D approx. © 1997-. Aluminum-containing antacids include Maalox and Gaviscon. Aspirin (Acetylsalicylic acid). Available for Android and iOS devices. Minimally clinically significant. Aspirin may lower vitamin C level in blood, tissue and white blood-cells. 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