I read all these studies, hear in the news, and see all these dumb lawsuit commercials about testosterone causing cardiovascular events, blood clots and many other things. I’m around Monroe….so if you know one, let me know! Estrogen is mainly created in men by an action of an enzyme called Aromatase. ?..i am going in gym daily and i feel good in general …all my blood results are perfect …///Again if i take the TRT will help me in general ? So far so good. I don’t know if using a more “natural” testosterone will give better results, but a friend of mine gets his T from a formulay pharmacy that creates, blends, or mixes a different type of testosterone that is promoted to be more natural to the human body. Yes he was great with laments terms, made it real easy to understand n absorb…. This combo may work for other people as well. And we had a large enough group to look at the impact of testosterone on cancer risk. Testosterone therapy has also been shown to be effective in the treatment of osteoporosis and in increasing muscle bulk and strength. And btw, before you decide to respond to this with more quackery, testimonials or fake research, know that I am a pharmaceutical scientist and won’t fall for your bogus statements. I went to a lower dose, began cod liver capsules…and my numbers went down to normal. Strange thing is I think I have found a compounding pharmacy in Houston Texas that will fill this Rx. neglected to mention that this was an interesting article to read. I’m 74 years old. It did not help. Andy – If you take testosterone, your hypothalamus will notice an abundance of testosterone in your system and will instruct your pituitary gland not to send LH and FSH to your testicles. My main hope is for stronger muscles and muscle mass but I wouldn’t mind the sexual benefits. I am very fit and workout 4 times a week . That should be all you need to reduce the estrogen in your body.,my husband takes 1mg of Anastrozole 2 times a week. I was Very active /hyper growing up. As a nurse I am very concerned with following my labs as most of these places don’t actually follow my labs. –Deep depression (with suicide ideology) This is an area that has tremendous research potential in the coming years.*. Not exactly. Next week I am going to donate some blood, to bring my RBC count down, and see if that will help. Best of luck to all of you. Was having panic attacks etc. A clinical research has found that testosterone injection through subcutaneous tissue, which is under the skin into the body fat, provide a steadier levels of testosterone and enhances sense of well-being. and because of that together with “Poor decision making (me in highschool, college etc) America is in the midst of an epidemic that is being under advertised and overlooked. They will cover generic t gel (pharmacy says it only comes in 1% gel), androderm, axiron, fortesta. Erectile dysfunction does not usually go along with it either, though certainly if somebody has less sex drive or less interest, it’s more of a challenge to get a good erection. Really, you guys read/think too much. My T levels dropped from a low of around 200 on a 800+ scale to under 100 after I stopped using the gel. I am living proof that one can inject 10 times the recommended rate for the better part of a decade with no probs. Viagra does not increase nor contribute to the sex drive. It just extends the time for recovery and the time you will feel crappy. Other studies have shown that it improves mood. 2009 had heart attack, placed coronary stent, everything okay. But last year (in september) I started using vitamine D (10 000 IU) and K2 (180 mcg), combined with magnesium (200 mg malate) and zinc (25 mg malate and piccolinate) every night, and since then I no longer have low testo in the winter, and is feeling like I do in the summer and have normal testo levels. Any advice would be appreciated. because he thinks i look “healthy”. Glad I had insurance, because it is EXPENSIVE!!!!! Don’t waste your time with the gel, the Injectable is far superior. i will be 38 next month and am a little “lost” about all of this. But, not many people know about the methadone situation. I keep myself fit, gym twice a week and martial arts twice a week and found my energy levels were depleting and didn’t seem to recover quickly the next day. But every single study of whether testosterone is bad for the heart has been negative, and what people haven’t pointed out in most of those negative studies is that there may be a beneficial effect. If you subscribe to any of our print newsletters and have never activated your online account, please activate your account below for online access. I actually thought oh well this is what happens when you get older. Or is my body constantly requiring high levels of steroid as this medicine starts dropping my levels to a mid range of 450 units after 6th week till what I know. With an initial level of 241 no doctor here at that time, would even consider HRT as I was only 35ish at the time. That makes drugs like clomiphene citrate one of only a few choices for men with low testosterone who want to father children. Can you give me any info I can pass along to my doctor? My doctor recommended a compounding Pharmacy that made a cream and it was perfect. It is serious business. Take Anastrozole EOD if possible. . Absolutely applaud. Our bodies have a lot more hormones to balance than just testosterone and estradiol and the crash can be a little rough if you have to stop. Switched to weekly injections (at home)2 years ago and its been great. Google Testosterone pellets. Side note, insurance rarely will cover it and cause a long paper trail to even approve it which is unfortunate and disheartening. The most commonly used testosterone preparation in the United States — and the one I start almost everyone off with — is a topical gel. It turns out that a third of those men will have adequate erections with testosterone-replacement therapy alone and another third will have adequate erections with the pills and testosterone combined. I am 31, been on HRT for about 6 months now. There are no uncertainties or limitations when it comes to delivery of the drug. BCBS has decided to stop covering androgel, natesto, testim, and vogelxo in 2016. Been taking prescribed Testosterone for more than 4 years now and the benefits have been nothing short of amazing!! I am 51 male. Earlier this year i was diagnosed with osteoporosis (-3.9 t-score). So she started me on testosterone injections weekly 200mg . So to those who have found a Dr. that actually listens and works with your individual issues, kuddos. Hormone therapy and radiation may help with certain prostate cancer, Unlocking the mystery of chronic pelvic pain syndrome, Women with DCIS at increased risk for breast cancer death, A silent condition may be taking a toll on your health. In general have your Total T Levels checked immediately prior to your next injection to see how low it gets, then have it rechecked 48-72 hours later to see it’s peek level. Low T is a serious problem that has a serious cure. There’s lots of money at stake here, and lets face it, most doctors are more interested in becoming millionaires than your health. Now 57 and still cancer free. This is a result that many men get when they get T injections. All rights reserved. The issue was more than likely caused by estrogen overload and the measurement of ultra sensitive estradiol would prove it. Nice overview with solid, practical advice. Re-doing blood work again just to be sure in the next week or so, and will post updates then as things progress. I’ve gone to pellet implants for the past 7 years. Testosterone undecanoate is a long-lasting ester, and physicians typically try to inject on an every 6 week or 2 month protocol. I am 44 years old and I workout 4-5 days a week hard. He has no concerns that the T will cause me to get prostate cancer again. It’s all how your body reacts but every 2 weeks is just plain too far apart as the product is relatively ineffective after 10 days. At the end of the study period, the researchers see who developed prostate cancer and who didn’t. After you stop testosterone therapy, you will likely also be put on a regimen of vitamins and nutritional supplements designed to stimulate your body to increase your natural testosterone output. Turns out I was around 189, and it explained a lot. I don’t want to be on it now though I worry about osteoporosis. you can recover from the prostate diseases softly and has no side effect. Wang C, Cunningham G, Dobs A, et al. I have had low T for a few years now. Dustin, I was reading through the comments and thought I’d check in to see how long you stuck with it and how it worked. Increase to a full dose of progesterone: I do hope the medical field catches up with the times and stops relying on archaic info. Am I playing with fire or doing the right thing and have you had other patients with similar histories? I was so bad with my nerves I ended up in the ER while on vacation . Then after 7 days or so all gone bad nerves started back up . Then follow up estrogen lab tests for any necessary Anastrozole dose adjustments. For most men, the benefits of TRT certainly outweigh the risks. The glucocorticoid tapering and stress dose pathway outlines the steps to be taken when a child on steroids needs stress dosing or tapering. Now, I cannot find a doctor who even knows the protocol for tapering off the TRT. I am now 41 and feel great , go to Doctor twice a year for bloodwork and all is well. In summary, I started off very secretive of the fact I was on HRT, until I decided this was a bigger issue than myself and have become an advocate for research and acceptance among men in our society today. PMID: 15126525. Then he gave me the injection of 200mg test . I went back to the doctors yesterday to get the results of my blood test and my testosterone levels have practically doubelled, they are now 20.4! Anyone who reads your comment will waste at least 20 seconds of their life. My level was 429 the first time and the second time 356. Clomid benefits tapering off ... After about a month on clomid therapy, my testosterone went from 150 to 580. When i started felt I was 17, (I was 50))I did everything possible and passed for type A, and physiologically, things seem to heal faster. But now at my first year appointment, my testosterone measured in the mid 300. Test enanthate half life is 5,25 days (1/2 * ester chain length) this means 200 mg will be almost 0 after 2 weeks and nowhere near to be found after 4. a healthy adult at 20 produces an amount of 200 mg per week more or less. See the guevosdoce in the Dominican Republic or other areas where the enzyme that converts Test into Dihydrotest is missing. Didnt start yet since the told me tbey dont check for estradiol they do “standard trt”. Read the above article. One reported no change in average testosterone until after 2 p.m. And I am forced to take the next shot by the beginning of 6th week. Big move for me!! I am kind of anxious, but my T levels are non-existent. Unlike previous studies of HRT, which had been observational in nature, the WHI was a double-blind, randomized controlled trial. Unfortunately, the doctor was asked to leave the practice and his replacement refuses to use the injections on me. I get samples of Testim every now and then, it has a manly woody fragrance that women like. The count is just over the limit, not by much but it is on the high side especially compared to where my typical levels used to be. It’s a great resource for men like us. Doctors in the USA have no clue what they are doing. 2 killers of testosterone are chronic stress and lack of sleep. My husband started on Androforte cream about 3 weeks ago. At the time, that rate of prostate cancer in men with normal PSA was several times higher than anything published previously, and it approximated the risk of men who had an elevated PSA or an abnormal DRE. I’ve also noticed more sexual interest (closer to levels when younger – now 65) and get ‘harder’ when I do get an erection. [Editor’s note: In December 2009, the brand name of the drug in the United States was changed to Aveed. And what studies do you have to prove that it causes cancer other than you found out the “hard way”? My sex drive is on fire. Libido also fell from “strong” to “zero”. Original Levels 206 total and 3.5 free. Isn’t it Dihydrotestosterone that causes the gonads to grow? I have been doing this for a few years and my levels remain good. AU Bhasin S, Brito JP, Cunningham GR, Hayes FJ, Hodis HN, Matsumoto AM, Snyder PJ, Swerdloff RS, Wu FC, Yialamas MA SO J Clin Endocrinol Metab. There was actually a study overseas that said men could benefit with TRT at 600mg per week, although you will never see that happen with American doctors . Dr. advised HRT. This is now day three and I feel much better. I will contact the trt clinic in order to start my trt as they have much more experience with these things. The issue is the type of hormone used and doctors not knowing what they are doing. It’s being found too often that hypogonadism is pared with another abnormality of the endocrine system called Hypothyroidism which causes intense fatigue and even alzheimer like cognitive disruption. Some drugs can help restore normal hormonal balances and mitigate symptoms such as pain and depression. Over a period of a couple years I used Androgel and then Axiron. The prostate has shrunk to a much smaller size and the PSA has been undetectable for 20 years. Even a biopsy seems to have problems. In 2002, the federally sponsored Women’s Health Initiative (WHI) stopped its hormone replacement therapy (HRT) trial (estrogen plus progestin), which included more than 16,000 women, three years early because those taking the pills had an increased risk of developing breast cancer and blood clots, and an increased risk of suffering a stroke or heart attack than those taking a placebo. I feel GREAT! Anyone who reads your comment will waste at least 20 seconds of their life. Most melanomas come in the form of a new spot on the skin, not changes to an existing mole. Been unable to work for 2 years. How long can I keep this treatment up? Anyways I’ve been prescribed depo testosterone 200ml bottle. and do think the hair will grow back? I have had BPH for years. So, I extended the injection interval to 18 days instead of 15 days. Now I’m wondering if I can get thru this and stop taking it alltogether however I already know I’m seeing signs of being forgetful, lack of energy and foggy brain. Are there studies (risks) to long-term TRT? Any mention of products or services is not meant as a guarantee, endorsement, or recommendation of the products, services, or companies. Strength is now maybe 45% and I have more acne (back and shoulders). I am disappointed sufficiently to decide not to continue the program. I intend to get back to Androgel. You can look for diabetes patient education material on how to administer insulin injection to be used for testosterone injection or hCG. This is not the case for any of the comments I have read. And then there are things like maca(a plant that you can get in powder form) that hightens libido but not like zinc it doesnt highten the testosteron level. Testosterone treatment is controversial for men and even more so for women. Simply use blue light blocking glasses or F.lux from the play store. He is scheduled to return to practitioner for a refill on his gel prescription and we, his family, are hoping that he may be taken off this medication which has drastically changed the man I have known for nearly 20 years. I was wondering if tongkat and myomin would be helpful with lowering estrogen and increasing testosterone. This tapering guide is a compilation of medical information available and patient experience. Aromason will do same but clomid is more potent. I’ll stay on it until and if negative signs/symptoms arise. There needs to be a study created to test all of these side effects and posable treatments like estrogen lowering drugs and HCG for maintaining Testicle size. . Good luck. Prior to the medication, all was well and happy. It does. This year at my class reunion was a glaring example…..no doubt I looked younger than anyone, but it is sooo much more than just very that. In this article I detail what I wish somebody taught me before I started using anabolics about the ideal testosterone dosage to use during a bulking phase.. Now I have a low T blood test along with symptoms of Low T. I am familiar with the concept of testosterone replacement therapy “feeding the fire.” But I also am aware of numerous studies that say that there is no danger from testosterone therapy to one that had/has prostate cancer. i can live with a low normal, but less would not not be acceptable. Testosterone: Its Role in the Development of Prostate Cancer and Potential Risks from Use as Hormone Replacement Therapy. It’s amazing stuff and your doctor will not send you for a blood test unless you ask for one and test for testosterone. Dr. Abraham Morgentaler, an associate professor of surgery at Harvard Medical School and the director of Men’s Health Boston, specializes in treating prostate diseases and male sexual and reproductive difficulties. PMID: 11445632. This whole experience has been incredible and very positive with the only one psychological effect and no other physical side effect. Journal of Clinical Endocrinology and Metabolism 2002;87:5001–7. No one told me I … But after reading your article I must conclude that the odds are not so bad and that a little higher testosterone can be a good thing. What can you suggest for me taking testosterone and it making my blood too thick? I mean, the drugs cost $500 a month, although my cost is less. I would be glad if you could advice me of the risk of stopping the treatment. Thinking that weekly injections is BEST bet…, But when i was on the combo herbs got my levels from 100 to 550 on my own in 4months. Since then i have had multiple blood work done to establish testosterone levels and other relevant tests e.g. . She started trying about a drop a day to see if her libido would improve, and it did, dramatically, and also her moods and patience. He is the best. Yes, I loved all the improvements in energy and sex drive; however, I also developed a side effect–polycythemia, a high red blood cell count, which put me at risk for heart attack and stroke. Urologist put me on androgel. Mohr BA, Feldman HA, Kalish LA, et al. Studies have shown that testosterone-replacement therapy may offer a wide range of benefits for men with hypogonadism, including improved libido, mood, cognition, muscle mass, bone density, and red blood cell production. However an endocrinologist here refuses to consider TRT claiming serum testosterone results of 10.7 nmol/L are not sufficiently low to begin treatment or even a trial to see if this would improve the osteoporosis. Although, frankly, in a review that I wrote in the New England Journal of Medicine* where we reviewed as much of this as we could, we found no cases of stroke or severe clotting related to testosterone therapy. I need an answer regarding getting testoroene after having your Prostate removed. My question is.. Do you have to stop taking testosterone eventually or can you keep taking it as a supplement in a regular basis along the rest of your live? I am 35 and had the non sexual symptoms for awhile now( weight gain/muscle loss, extreme fatigue, lack of clarity/concentration) I got my testosterone levels checked last week and it was 35.4 ng. I feel like I did when I was 30 including a very healthy dream cycle about my wife. Only two medications needed. My name is Louis and I have been healthy for awhile and on Testostrone Injections (bi-weekly) but now I have developed RHABDOMYOLYSIS, Doctors have told me I am working out to hard, HELL I HAVENT WOKED OUT AT ALL! Good evening.. I tried patches, but they were too much of a hassle for me especially when you start to work out more. Apparently I am one of those men who do not absorb the gel very well. Was on injections prior and that got old. At the time I was on 150mg IM with half a dose or 0.5mL twice weekly to avoid the “roller coaster”. He doesn’t have to take a pill in anticipation of having sex. After several injections I felt great , muscles in legs came back , lots of energy everything good . Yes estrogen keeps arteries supple. I became concerned and stopped using them. Occult Prostate Cancer in Men with Low Serum Testosterone Levels. Dr Rand McClain, a TRT doctor in the US whom is often interviewed on YouTube explains how many of his clients wanting to stop TRT have just came off cold turkey and suffered no major repercussions. Effects of Testosterone on Body Composition, Bone Metabolism and Serum Lipid Profile in Middle-aged Men: A Meta-analysis. I’m thinking that this is being caused by the TRT and my body producing less of its own testosterone and other hormones? My T at start was 130. I am going to start, my endocrinologist More rigorous appraisal of testosterone’s efficacy and safety using RCTs published during the last three years. He is going to bump me up to 300mg q2 weeks and do a level 2 days after first injection and 1 day before next shot. I’m not sure how one can do this and another cannot especially if they have compounding capabilities. SHGB =70.6. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. The doctor took me down to twice/two applications a day, now I was at 600. I suffered a blood clot between my knee and my groin (right leg) in January, 2017. I am not sure what to take. (It’s already approved in many other countries.) I was told by my dr. That I needed to start TRT right away as low t can effect a lot different things in your body. But diet hasn’t been studied thoroughly enough to make any clear recommendations. A study by the Veterans Administration reported about a year ago showed low testosterone levels were associated with a dramatically increased mortality rate. In its 2004 report, the Institute of Medicine (IOM) committee studying the need for clinical trials of testosterone-replacement therapy noted that only 31 placebo-controlled studies had been done in older men, with the largest one enrolling just 108 participants. I use 250 at the lowest and 1000 mgs a week and sometimes 1200 mgs weekly. Way short of what we as men need. She has threatened to reduce or stop my Testosterone medicine once I’m into my mid sixties!!. Could there be a political correctness crept in the scientific community that is hindering newly invigorated research in this area? Men may experience other symptoms, such as more difficulty achieving an orgasm, less-intense orgasms, a smaller amount of fluid from ejaculation, and a feeling of numbness in the penis when they see or experience something that would normally be arousing. Last April, I totally stopped Androgel and within 2 months my Testosterone was under 20 (really) and PSA was virtually zero. Well, we found prostate cancer in one of the first men with low testosterone we biopsied, even though his PSA level and digital rectal exam (DRE) were normal. I have felt my strength and energy fade over the last 10 years to the point that i now take a nap in the afternoon. This works like estrogen to prevent bone loss. Here’s What You Should Know about Testosterone Production, The Effect of HCG Therapy with Testosterone in Preserving Fertility, Libido and Testicle Size, Top 7 Reasons to Naturally Increase Testosterone Levels, Revealed: Subcutaneous Testosterone Injections Offer More Favorable Effects, Linking Erectile Dysfunction and Low Testosterone, 1.0 mg Arimidex (Anastrozole) per week in divided doses, 250 IU Human Chorionic Gonadotropic injected subcutaneously every other day, 100 mg testosterone enanthate or cypionate given per week, could be two or more depending on doctor’s advise. The only reason it ended in three months, was due to no more medicine. The goal the Production of CBD tapering kratom was always already .The Use of the medium is in the process either shorter or longer - depending on the desired Results and the different individual Effects on you. That’s why you also need to take a serm,an aromatase inhibitor,HCG and test more than once a year .Testosterone by itself is not good enough and problems will develop with several functions in time.These can help maintain good balance. Is the risk higher taking gel or not. After 90 days, it seemed like the Andro Gel kind of stopped having it’s effect. and i can not do my studies or anything properly that i want to do. Secondly, the reduction or the complete blocking of estrogen would remove the one hormone that prevent s hardening of the arteries. My total T fluctuates between 500 and 1000 and my E2 has been staying under 30 with the help of Arimidex 0.5 mg every 3.5 days. My weight increased a .little since beginning therapy. It’s shocking how many men experience symptoms of Low Testosterone today versus just 10 years ago. 49Yr old who had to take R even young person ’ s is universally accepted, none. 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